2008 Amendments to the National Academies' Guidelines for by National Research Council, Institute of Medicine, Board on

By National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Board on Life Sciences, Human Embryonic Stem Cell Research Advisory Committee

In 2005, the nationwide Academies published the document instructions for Human Embryonic Stem telephone examine, which provided a standard set of moral criteria for a box that, as a result absence of finished federal investment, was once missing nationwide criteria for research.

In order to maintain the information modern, given the speedy speed of medical advancements within the box of stem telephone learn, the Human Embryonic Stem cellphone study Advisory Committee used to be validated in 2006 with help from The Ellison scientific starting place, The Greenwall starting place, and the Howard Hughes clinical Institute.

As it did in 2007, the Committee pointed out matters that warranted revision, and this e-book addresses these matters in a moment set of amendments. most significantly, this booklet addresses new clinical advancements in reprogramming of somatic cells to pluripotency through including a brand new part and revising different suitable sections of the Guidelines.

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Extra info for 2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

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In addition: (iii) No animal into which hES cells have been introduced such that they could contribute to the germ line should be allowed to breed.  In particular, people whose research involves hES cells should work closely with oversight bodies, demonstrate respect for the autonomy and privacy of those who donate gametes, blastocysts, or somatic cells and be sensitive to public concerns about research that involves human embryos. S. federally funded research. 0 of the Guidelines. 1 of the Guidelines.

Park, In-Hyun, Rui Zhao, Jason A. West, Akiko Yabuuchi, Hongguang Hu, Tan A. Ince, Paul H. Lerou, M. William Lensch, and George Q. Daley. 2008. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451: 141-146. Streiffer, Robert. 2008. Informed Consent and Federal Funding for Stem Cell Research, Hastings Center Report 38(3): 40-47. Takahashi, Kazutoshi, and Shinya Yamanaka. 2006. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors.

Iii) Research in which the identity of the donors of blastocysts, gametes, or somatic cells from which the hES cells were derived is readily ascertainable or might become known to the investigator. 3(c) hES cell research that should not be permitted at this time The following types of research should not be conducted at this time: (i) Research involving in vitro culture of any intact human embryo, regardless of derivation method, for longer than 14 days or until formation of the primitive streak begins, whichever occurs first.

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